In a client with HIV, a CD4-T-cell count of 180 cells/mm3 indicates what state of the immune system?

A CD4-T-cell count of 180 cells/mm3 indicates severe immunosuppression in a client with HIV. This is significant because CD4-T cells play a crucial role in the immune system, particularly in orchestrating the body's response to infections. Normal CD4 counts typically range from 500 to 1,500 cells/mm3. When the count falls below 200 cells/mm3, as is the case here, the individual is considered to be at a high risk for opportunistic infections and other complications related to HIV/AIDS.

The state of severe immunosuppression indicates that the body is not able to mount an effective immune response against pathogens, which is a critical aspect of managing HIV infection. This level reflects the progression of the disease and signals the need for more aggressive treatment and monitoring, as the risk for infections and other health issues rises significantly.

In contrast, improved immunity would suggest a higher CD4 count that indicates recovery or effective management of HIV, normal immune function is characterized by higher counts, and minimal immune response would generally refer to a situation of moderate immunosuppression, which does not apply here.