When caring for a client receiving cisplatin for bladder cancer, what action should the nurse prioritize if the client reports fatigue?

When a client undergoing treatment with cisplatin reports fatigue, the most appropriate action for the nurse is to check the results of the client's most recent complete blood count (CBC). This is crucial because fatigue can be indicative of several underlying issues related to the effects of chemotherapy, one of the most common being anemia. Cisplatin, like many chemotherapeutic agents, can lead to bone marrow suppression, resulting in decreased red blood cell production. Consequently, monitoring the CBC helps the nurse determine if the fatigue is due to anemia, which can then guide subsequent interventions, such as potential blood transfusions or adjustments to the treatment plan.

Furthermore, while other assessments related to hypersensitivity reactions, hypercalcemia, or hepatomegaly may be important in their own contexts, they are not the immediate priority in this situation. Fatigue is most commonly connected to blood cell counts in individuals undergoing chemotherapy, making the CBC the most relevant assessment to address the client's reported symptoms effectively.